gene

KCNIP1

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about KCNIP1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	KCNIP1
Chromosome	5q32
Function	is a member of the neuronal calcium sensor (NCS) family of EF-hand calcium-binding proteins.
Subcellular Localization	Within neurons, KCNIP1 localizes to:
Exons	8
Ensembl ID	ENSG00000178537
GeneCards	KCNIP1
Human Protein Atlas	KCNIP1
Isoform 1	Full-length, brain-enriched
Isoform 2	Lacks exon 2, cardiac-preferred
Isoform 3	Alternative C-terminus
Isoform 4	Truncated, testis-specific
Isoform 5	Neuron-specific
Trafficking enhancement	Facilitates Kv4 protein forward trafficking from ER to plasma membrane
Gating modification	Slows inactivation kinetics, accelerates recovery from inactivation
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

kcnip1

gene · 1349 words

→

KCNIP1 Protein

protein · 618 words

→

Pathway Diagram

graph TD
    KCNIP1["KCNIP1"]
    neurodegeneration["neurodegeneration"]
    KCNIP1 -->|"implicated_in"| neurodegeneration
    style KCNIP1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity