gene

KCNIP3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KCNIP3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

KCNIP3 (DREAM) is a calcium-binding protein that regulates Kv4 potassium channels and acts as a calcium-dependent transcriptional regulator. Important for neuronal excitability, pain signaling, and synaptic plasticity.

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🧬 Gene Info

Gene Symbol	KCNIP3
Aliases	DREAM
Chromosome	2q11.2
Function	is a multifunctional calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family.
Molecular Weight	29 kDa
Amino Acids	256 aa
Exons	7
UniProt ID	Q9Y587
NCBI Gene ID	28998
Ensembl ID	ENSG00000153250
OMIM	604662
GeneCards	KCNIP3
Human Protein Atlas	KCNIP3
Exon 1	5' UTR and N-terminal region
Exons 2-6	Core coding sequence including EF-hand domains
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KCNIP3 — AlphaFold Q9Y587 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KCNIP3

gene · 1867 words

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Pathway Diagram

graph TD
    KCNIP3["KCNIP3"]
    neurodegeneration["neurodegeneration"]
    KCNIP3 -->|"implicated_in"| neurodegeneration
    style KCNIP3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KCNIP3 in their description or question text

No additional research found