gene

KCNJ11

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about KCNJ11: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Potassium inward rectifier gene KCNJ11 (Kir6.2)

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🧬 Gene Info

Gene Symbol	KCNJ11
Full Name	Potassium Inwardly Rectifying Channel Subfamily J Member 11
Aliases	Kir6.2
Chromosome	11p15.1
Function	is an octameric complex comprising four Kir6.
Primary Expression	various brain regions including the hippocampus, cortex, and substantia nigra [6]
UniProt ID	Q14654
NCBI Gene ID	3769
Ensembl ID	ENSG00000187486
OMIM	600937
GeneCards	KCNJ11
Human Protein Atlas	KCNJ11
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KCNJ11 — AlphaFold Q14654 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KCNJ11 Gene

gene · 1246 words

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Pathway Diagram

graph TD
    KCNJ11["KCNJ11"]
    neurodegeneration["neurodegeneration"]
    KCNJ11 -->|"implicated_in"| neurodegeneration
    style KCNJ11 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning KCNJ11 in their description or question text

No additional research found