gene

KCNS3

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about KCNS3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	KCNS3
Chromosome	2p24.2
Protein Type	Gene
Function	is a modulatory auxiliary subunit of voltage-gated potassium channels expressed predominantly in the nervous system.
Primary Expression	hippocampal pyramidal neurons, cortical pyramidal neurons, cerebellar granule cells, and certain interneuron populations[@bhattacharjee2003]
Molecular Weight	56 kDa
Amino Acids	502 aa
Exons	4
UniProt ID	Q9BQ92
NCBI Gene ID	3786
GeneCards	KCNS3
Human Protein Atlas	KCNS3
Kv9.1 (KCNS1)	Brain and spinal cord, modulatory subunit
Kv9.2 (KCNS2)	Brain and peripheral tissues, modulatory subunit
Kv9.3 (KCNS3)	Brain-predominant, modulatory subunit
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KCNS3 — AlphaFold Q9BQ92 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KCNS3 (Kv9.3)

gene · 1983 words

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Pathway Diagram

graph TD
    KCNS3["KCNS3"]
    neurodegeneration["neurodegeneration"]
    KCNS3 -->|"implicated_in"| neurodegeneration
    style KCNS3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning KCNS3 in their description or question text

No additional research found