gene

KCNV1

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about KCNV1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for KCNV1 Gene

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🧬 Gene Info

Gene Symbol	Potassium Voltage-Gated Channel Modifier Subfamily V Member 1
Chromosome	8p23.1
Protein Family	Kv channel beta subunit (KCNB) family
Protein Type	Channel
Function	encodes a regulatory beta subunit of voltage-gated potassium (Kv) channels.
Subcellular Localization	neuronal soma and proximal dendrites, with some expression in axons
Molecular Weight	50 kDa
Amino Acids	465 aa
UniProt ID	Q9NWV8
NCBI Gene ID	27040
Ensembl ID	ENSG00000167614
OMIM	609138
Brain Regions	High expression in hippocampus (particularly CA1 pyramidal neurons), cerebral cortex, cerebellum (Purkinje cells), and various subcortical nuclei.
Cellular Localization	Primarily localized to neuronal soma and proximal dendrites, with some expression in axons.
Development	Expression levels increase during postnatal development, coinciding with neuronal maturation and synaptogenesis.
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KCNV1 — AlphaFold Q9NWV8 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KCNV1 Gene

gene · 1572 words

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Pathway Diagram

graph TD
    KCNV1["KCNV1"]
    neurodegeneration["neurodegeneration"]
    KCNV1 -->|"implicated_in"| neurodegeneration
    style KCNV1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning KCNV1 in their description or question text

No additional research found