Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KIF13B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | KIF13B |
| Full Name | Kinesin Family Member 13B |
| Chromosome | 8p21.3 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 180 kDa |
| UniProt ID | Q9N2U8 |
| NCBI Gene ID | 25803 |
| Ensembl ID | ENSG00000102743 |
| OMIM | 607349 |
| GeneCards | KIF13B |
| Human Protein Atlas | KIF13B |
| ATP-dependent movement | KIF13B hydrolyzes ATP to generate force for movement along microtubule tracks, typically moving toward the plus end of microtubules |
| Processive motility | The protein can take numerous steps along the microtubule track without dissociating, making it efficient for long-range transport |
| Cargo binding | KIF13B contains specific domains that recognize and bind to diverse cargo molecules, including vesicles, protein complexes, and membrane organelles |
| N-terminal motor domain | Catalyzes ATP hydrolysis and microtubule binding |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
KIF13B["KIF13B"]
neurodegeneration["neurodegeneration"]
KIF13B -->|"implicated_in"| neurodegeneration
style KIF13B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning KIF13B in their description or question text
No additional research found