gene

KIF20B

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about KIF20B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Gene profile: KIF20B (MPHOSPH1), a kinesin-6 family protein involved in mitosis and mitochondrial dynamics

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🧬 Gene Info

Gene Symbol	KIF20B
Full Name	Kinesin Family Member 20B
Aliases	MPHOSPH1
Chromosome	10q23.31
Protein Family	Kinesin-6 (MKLP) subfamily
Function	encodes a protein of 1,628 amino acids, also known as MPHOSPH1 (M-phase phosphoprotein 1).
Primary Expression	Brain, mitotic cells
Molecular Weight	180 kDa
Amino Acids	628 aa
Exons	35
UniProt ID	Q9UG8G
NCBI Gene ID	9588
GeneCards	KIF20B
Human Protein Atlas	KIF20B
N-terminal motor domain (1-380 aa)	ATP-binding site and microtubule interaction interface
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KIF20B — AlphaFold Q9UG8G Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KIF20B — Kinesin Family Member 20B

gene · 644 words

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Pathway Diagram

graph TD
    KIF20B["KIF20B"]
    neurodegeneration["neurodegeneration"]
    KIF20B -->|"implicated_in"| neurodegeneration
    style KIF20B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning KIF20B in their description or question text

No additional research found