gene

KIF22

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KIF22: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Gene profile: KIF22 (KIDIN), a kinesin motor protein involved in chromosome dynamics, spindle assembly, and skeletal development

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🧬 Gene Info

Gene Symbol	KIF22
Full Name	Kinesin Family Member 22
Aliases	KIDIN
Chromosome	16p11.2
Protein Family	Kinesin-7 (CENP-E) subfamily
Function	encodes a protein of 805 amino acids, also known as KIDIN (Kinesin Family Member Involved in Development).
Primary Expression	Mitotic cells, developing bone
Subcellular Localization	kinetochores during mitosis
Molecular Weight	95 kDa
Amino Acids	805 aa
Exons	20
UniProt ID	Q9NRL3
NCBI Gene ID	11176
GeneCards	KIF22
Human Protein Atlas	KIF22
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KIF22 — AlphaFold Q9NRL3 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KIF22 — Kinesin Family Member 22

gene · 673 words

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Pathway Diagram

graph TD
    KIF22["KIF22"]
    neurodegeneration["neurodegeneration"]
    KIF22 -->|"implicated_in"| neurodegeneration
    style KIF22 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning KIF22 in their description or question text

No additional research found