gene

KIF25

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KIF25: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for KIF25 — Kinesin Family Member 25

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🧬 Gene Info

Gene Symbol	KIF25
Full Name	Kinesin Family Member 25
Chromosome	6q25.3
Function	Unlike conventional kinesins that transport cargo toward the cell periphery, kinesin-14 proteins often function in retrograde transport and microtubule organization within cells.
UniProt ID	[Q9Y5P8](https://www.uniprot.org/uniprot/Q9Y5P8)
Ensembl ID	ENSG00000129128
OMIM	604243
GeneCards	KIF25
Human Protein Atlas	KIF25
Cell cycle re-entry	Aberrant cell cycle activation in neurons is a feature of Alzheimer's disease
Microtubule dysfunction	Kinesin impairment contributes to axonal transport deficits in multiple neurodegenerative diseases
High expression	Testis, ovary, breast tissue
Estrogen-responsive tissues	Uterus, mammary gland
Proliferating cells	Elevated in dividing cells
Lower expression	Most adult tissues
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KIF25 — Kinesin Family Member 25

gene · 805 words

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Pathway Diagram

graph TD
    KIF25["KIF25"]
    neurodegeneration["neurodegeneration"]
    KIF25 -->|"implicated_in"| neurodegeneration
    style KIF25 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KIF25 in their description or question text

No additional research found