gene

KIF26B

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KIF26B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Gene profile: KIF26B, a divergent kinesin with critical roles in brain development and cortical patterning

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🧬 Gene Info

Gene Symbol	KIF26B
Full Name	Kinesin Family Member 26B
Chromosome	1q44
Protein Family	Kinesin-11 (unconventional)
Function	encodes a protein of 1,864 amino acids, making it one of the largest kinesin family members.
Primary Expression	Brain, particularly cortex
Molecular Weight	210 kDa
Amino Acids	864 aa
Exons	45
UniProt ID	Q7Z3V4
NCBI Gene ID	27151
GeneCards	KIF26B
Human Protein Atlas	KIF26B
N-terminal motor domain (1-360 aa)	Contains conserved ATP-binding and microtubule interaction motifs
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KIF26B — AlphaFold Q7Z3V4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KIF26B — Kinesin Family Member 26B

gene · 615 words

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Pathway Diagram

graph TD
    KIF26B["KIF26B"]
    neurodegeneration["neurodegeneration"]
    KIF26B -->|"implicated_in"| neurodegeneration
    style KIF26B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning KIF26B in their description or question text

No additional research found