gene

KIF2C

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about KIF2C: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

KIF2C Gene

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🧬 Gene Info

Gene Symbol	KIF2C
Full Name	Kinesin Family Member 2C
Chromosome	1p34.2
Function	KIF2C is a mitotic kinesin with microtubule-depolymerizing activity.
Primary Expression	neurons and may play roles in neuronal development and axonal transport
UniProt ID	[Q9UBX6](https://www.uniprot.org/uniprotkb/Q9UBX6/entry)
GeneCards	KIF2C
Human Protein Atlas	KIF2C
Kinesin Superfamily	Other kinesins (KIF5, KIF11, KIF1A) with distinct roles in neuronal function
Microtubule-Associated Proteins	Tau and MAP2, which interact with microtubules and are dysregulated in neurodegeneration
Aurora Kinases	Regulators of KIF2C phosphorylation and activity
Tubulin	The structural component of microtubules affected by KIF2C depolymerization activity
Associated Diseases	Cancer (relevant to neurodegeneration research)
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KIF2C Gene

gene · 624 words

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Pathway Diagram

graph TD
    KIF2C["KIF2C"]
    neurodegeneration["neurodegeneration"]
    KIF2C -->|"implicated_in"| neurodegeneration
    style KIF2C fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning KIF2C in their description or question text

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