Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KIF7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | KIF7 |
| Full Name | Kinesin Family Member 7 |
| Chromosome | 15q26.1 |
| Function | KIF7 is a kinesin motor protein that plays crucial roles in the Hedgehog (Hh) signaling pathway, ciliogenesis, intraflagellar transport (IFT), brain development, and axonal guidance. |
| Molecular Weight | 200 kDa |
| Amino Acids | 380 aa |
| UniProt ID | Q8WVJ1 |
| NCBI Gene ID | 374654 |
| Ensembl ID | ENSG00000129226 |
| OMIM | 611254 |
| GeneCards | KIF7 |
| Human Protein Atlas | KIF7 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
KIF7["KIF7"]
neurodegeneration["neurodegeneration"]
KIF7 -->|"implicated_in"| neurodegeneration
style KIF7 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning KIF7 in their description or question text
No additional research found