Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KPNA1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | KPNA1 |
| Full Name | Karyopherin Subunit Alpha 1 |
| Chromosome | 3q21.1 |
| Function | The KPNA1 gene encodes a protein that is expressed in multiple brain regions including Brain, Spinal cord, Neurons. |
| Primary Expression | Brain, Spinal cord, Neurons |
| Molecular Weight | 53 kDa |
| UniProt ID | P52292 |
| NCBI Gene ID | 3836 |
| Ensembl ID | ENSG00000160310 |
| OMIM | 150550 |
| GeneCards | KPNA1 |
| Human Protein Atlas | KPNA1 |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
KPNA1["KPNA1"]
neurodegeneration["neurodegeneration"]
KPNA1 -->|"implicated_in"| neurodegeneration
style KPNA1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning KPNA1 in their description or question text
No additional research found