protein

KV72PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KV72PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

The M-channel was first characterized in sympathetic neurons where its activation by muscarinic acetylcholine receptors (M1/M3) caused membrane hyperpolarization—a phenomenon that gave the channel its name ("M" for muscarine).

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🔬 Protein Info

Gene Symbol	KV72PROTEIN
Protein Family	Voltage-gated potassium channel family
Protein Type	Channel
Function	is a voltage-gated potassium channel subunit that forms the M-channel, a critical regulator of neuronal excitability in the central and peripheral nervous systems.
Molecular Weight	75 kDa
Amino Acids	240 aa
UniProt ID	O43520
GeneCards	KV72PROTEIN
Human Protein Atlas	KV72PROTEIN
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: KV72PROTEIN — AlphaFold O43520 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Kv7.2 Potassium Channel

protein · 3469 words

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Pathway Diagram

graph TD
    KV72PROTEIN["KV72PROTEIN"]
    neurodegeneration["neurodegeneration"]
    KV72PROTEIN -->|"implicated_in"| neurodegeneration
    style KV72PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning KV72PROTEIN in their description or question text

No additional research found