protein

KV73PROTEIN

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about KV73PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🔬 Protein Info

Gene Symbol	KV73PROTEIN
Full Name	Potassium voltage-gated channel subfamily Q member 3
Protein Family	Voltage-gated potassium channel (KCNQ) family
Protein Type	Channel
Function	is a voltage-gated potassium channel subunit that plays a critical role in regulating neuronal excitability.
Primary Expression	the central nervous system, where they form heterotetrameric channels that produce the M-current, named for its inhibition by muscarinic agonists
Molecular Weight	90 kDa
Amino Acids	400 aa
UniProt ID	O43525
GeneCards	KV73PROTEIN
Human Protein Atlas	KV73PROTEIN
S1-S4	Voltage-sensing domain that detects changes in membrane potential
S5-S6	Pore-forming domain that conducts potassium ions
N-terminus	Cytoplasmic domain involved in subunit assembly and modulation
C-terminus	Large cytoplasmic domain (≈400 residues) containing sites for regulation
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: KV73PROTEIN — AlphaFold O43525 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Kv7.3 Potassium Channel

protein · 3781 words

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Pathway Diagram

graph TD
    KV73PROTEIN["KV73PROTEIN"]
    neurodegeneration["neurodegeneration"]
    KV73PROTEIN -->|"implicated_in"| neurodegeneration
    style KV73PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

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Related Research

Hypotheses and analyses mentioning KV73PROTEIN in their description or question text

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