Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about LRRTM1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Gene Symbol | LRRTM1 |
| Full Name | Leucine-Rich Repeat Transmembrane Neuronal 1 |
| Chromosome | 2p14 |
| Function | LRRTM1 encodes leucine-rich repeat transmembrane neuronal 1, a member of the LRRTM family of synaptic adhesion molecules. |
| Primary Expression | the brain: |
| Molecular Weight | 60 kDa |
| UniProt ID | Q9UHV9 |
| NCBI Gene ID | 26017 |
| Ensembl ID | ENSG00000162908 |
| OMIM | 610867 |
| GeneCards | LRRTM1 |
| Human Protein Atlas | LRRTM1 |
| PTPδ | Primary presynaptic interaction partner |
| PSD-95 | Postsynaptic density scaffolding protein |
| Synaptic plasticity | LRRTM1-dependent mechanism |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
LRRTM1["LRRTM1"]
neurodegeneration["neurodegeneration"]
LRRTM1 -->|"implicated_in"| neurodegeneration
style LRRTM1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning LRRTM1 in their description or question text
No additional research found