Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MAPK14/PRMT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Target | Relation | Type | Str |
|---|---|---|---|
| neurodegeneration | promoted: p38α Inhibitor and PRMT1 Activator Combination to Restore Physiological TDP-43 Phosphorylation-Methy | disease | 0.61 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| p38α Inhibitor and PRMT1 Activator Combination to Restore Ph | 0.615 | neurodegeneration | What is the therapeutic window between i |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-12 | 2 hypotheses Top: 0.615
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine meth [PMID:39817908] | Aikio M, Odeh HM, Wobst HJ, Lee BL, Chan | Cell Rep | 2025 | 0 |
| Identification of energy metabolism-related biomarkers for risk prediction of he [PMID:36304554] | Chen H, Jiang R, Huang W, Chen K, Zeng R | Front Cardiovasc Med | 2022 | 0 |
| Calcium-dependent methylation by PRMT1 promotes erythroid differentiation throug [PMID:31541584] | Liu MY, Hua WK, Chiou YY, Chen CJ, Yao C | FEBS Lett | 2020 | 0 |