Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MEK1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | MEK1 |
| Protein Family | MEK dual-specificity kinases |
| Protein Type | Kinase |
| Function | is a dual-specificity protein kinase that serves as a critical intermediate in the MAPK/ERK signaling cascade. |
| Molecular Weight | 43.4 kDa |
| Pathways | MAPK, MAPK signaling, mapk |
| UniProt ID | Q02750 |
| GeneCards | MEK1 |
| Human Protein Atlas | MEK1 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
MEK1["MEK1"]
neurodegeneration["neurodegeneration"]
MEK1 -->|"implicated_in"| neurodegeneration
style MEK1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MEK1 in their description or question text
No additional research found