gene

MEX3B

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about MEX3B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

MEX3B Gene

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🧬 Gene Info

Gene Symbol	MEX3B
Full Name	MEX3 RNA Binding Family Member B
Chromosome	11q22.2
Function	is an RNA-binding protein that plays critical roles in post-transcriptional gene regulation, innate immune signaling, and RNA metabolism[@buchetpoyau2002].
Subcellular Localization	[@dagostino2021]
UniProt ID	[Q8IZL8](https://www.uniprot.org/uniprot/Q8IZL8)
Ensembl ID	ENSG00000178297
GeneCards	MEX3B
Human Protein Atlas	MEX3B
Post-transcriptional regulation	Binds to specific mRNA sequences to regulate translation efficiency
mRNA stability	Modifies mRNA half-life through binding to 3' UTR regions
RNA granule localization	Participates in stress granules and processing bodies
RIG-I-like receptor (RLR) signaling	Modulates antiviral response signaling cascades
Interferon response	Regulates interferon-stimulated gene expression
Viral RNA sensing	Involved in cytoplasmic RNA detection pathways
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

MEX3B Gene

gene · 822 words

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Pathway Diagram

graph TD
    MEX3B["MEX3B"]
    neurodegeneration["neurodegeneration"]
    MEX3B -->|"implicated_in"| neurodegeneration
    style MEX3B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

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Related Research

Hypotheses and analyses mentioning MEX3B in their description or question text

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