gene

MFNG

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MFNG: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Analyses

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0Debates

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🧬 Gene Info

Gene Symbol	MFNG
Full Name	Manic Fringe
Chromosome	22q12.2
Protein Type	Transferase
Function	encodes a Golgi-localized glycosyltransferase that modifies Notch receptors by adding N-acetylglucosamine (GlcNAc) to O-fucose residues on the extracellular domain.
Subcellular Localization	the Golgi apparatus:
Gene Type	Protein-coding
Pathways	Notch, Notch signaling, Notch Signaling, Notch pathway
UniProt ID	Q9Y2T7
NCBI Gene ID	4242
Ensembl ID	ENSG00000177150
OMIM	602577
GeneCards	MFNG
Human Protein Atlas	MFNG
Transcript Length	1,218 bp
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: MFNG — AlphaFold Q9Y2T7 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    MFNG["MFNG"]
    neurodegeneration["neurodegeneration"]
    MFNG -->|"implicated_in"| neurodegeneration
    style MFNG fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity