Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MFSD1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Major Facilitator Superfamily Domain Containing 1 - a putative solute carrier transporter implicated in hereditary spastic paraplegia and neuronal function
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| Gene Symbol | MFSD1 |
| Aliases | Major Facilitator Superfamily Domain Containing 1 |
| Chromosome | 6p21.1 |
| Function | is a member of the Major Facilitator Superfamily (MFS), one of the largest and most diverse superfamily of membrane transporters found in all kingdoms of life [1/https://pubmed. |
| Primary Expression | neurons throughout the central nervous system, with particularly high expression in the [cortex)(/brain-regions/cortex), cerebellum, brainstem, and [s |
| Amino Acids | 550 aa |
| Ensembl ID | ENSG00000132514 |
| GeneCards | MFSD1 |
| Human Protein Atlas | MFSD1 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
MFSD1["MFSD1"]
neurodegeneration["neurodegeneration"]
MFSD1 -->|"implicated_in"| neurodegeneration
style MFSD1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MFSD1 in their description or question text
No additional research found