protein

MGLUR4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MGLUR4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Metabotropic glutamate receptor 4 (mGluR4/GRM4) is a Group III GPCR highly expressed in the cerebellum and basal ganglia, with therapeutic potential in Parkinson's disease, epilepsy, and neurodegenerative disorders.

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🔬 Protein Info

Gene Symbol	MGLUR4
Aliases	mGluR4/GRM4
Chromosome	6p21.3
Protein Type	Receptor
Function	mGluR4 is a Group III metabotropic glutamate receptor expressed predominantly in the cerebellum and basal ganglia.
Molecular Weight	110 kDa
Exons	9
GeneCards	MGLUR4
Human Protein Atlas	MGLUR4
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

mGluR4 Protein

protein · 747 words

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Pathway Diagram

graph TD
    MGLUR4["MGLUR4"]
    neurodegeneration["neurodegeneration"]
    MGLUR4 -->|"implicated_in"| neurodegeneration
    style MGLUR4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MGLUR4 in their description or question text

No additional research found