MME

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolMME
Namemembrane metalloendopeptidase
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the

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