Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MS4A3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | MS4A3 |
| Full Name | Membrane Spanning 4-Domains A3 |
| Chromosome | 11q12.2 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | hematopoietic cells and, to a lesser extent, in various tissues including the brain |
| Molecular Weight | 30 kDa |
| Amino Acids | 238 aa |
| UniProt ID | [Q9H3Y6](https://www.uniprot.org/uniprot/Q9H3Y6) |
| Ensembl ID | ENSG00000166926 |
| GeneCards | MS4A3 |
| Human Protein Atlas | MS4A3 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
MS4A3["MS4A3"]
neurodegeneration["neurodegeneration"]
MS4A3 -->|"implicated_in"| neurodegeneration
style MS4A3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MS4A3 in their description or question text
No additional research found