MTOR

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolMTOR
Namemechanistic target of rapamycin kinase
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This kinase is a component of two distinct complexes, mTORC1, which controls protein synthesis, cell growth and proliferation, and mTORC2, which is a regulator of the actin cytoskeleton, and promotes cell survival and cell cycle progression. This protein acts as the target for the cell-cycle arrest a

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