Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Major Congenital Malformations: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Valproate | risk_factor_for | drug | 0.95 |
| Prenatal Exposure to Antiseizure Medications | associated_with | process | 0.92 |
| Carbamazepine | risk_factor_for | drug | 0.90 |
| Valproate | correlates_with | drug | 0.90 |
| Phenobarbital | correlates_with | drug | 0.90 |
| Carbamazepine | correlates_with | drug | 0.90 |
| Levetiracetam | protects_against | drug | 0.88 |
| Oxcarbazepine | protects_against | drug | 0.88 |
| Lamotrigine | protects_against | drug | 0.88 |
| Phenobarbital | risk_factor_for | drug | 0.85 |
| Phenytoin | risk_factor_for | drug | 0.80 |
| Topiramate | risk_factor_for | drug | 0.78 |
| Lamotrigine | risk_factor_for | drug | 0.75 |
| Levetiracetam | risk_factor_for | drug | 0.70 |
| Oxcarbazepine | risk_factor_for | drug | 0.68 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||