Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NALCN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | NALCN |
| Full Name | Sodium Leak Channel, Non-selective |
| Aliases | Page for NALCN |
| Chromosome | 13q33.3 |
| Protein Type | Channel |
| Function | NALCN encodes a voltage-independent, non-selective cation channel that conducts a persistent sodium leak current. |
| Primary Expression | the nervous system: - Brain (cortex, hippocampus, cerebellum) - Spinal cord (motor neurons) - P |
| UniProt ID | Q8IU68 |
| NCBI Gene ID | 79654 |
| Ensembl ID | ENSG00000186868 |
| GeneCards | NALCN |
| Human Protein Atlas | NALCN |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
NALCN["NALCN"]
neurodegeneration["neurodegeneration"]
NALCN -->|"implicated_in"| neurodegeneration
style NALCN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity