protein

NAV12PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NAV12PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

The *SCN1A* gene is located on chromosome 2q24 and encodes a protein of approximately 2000 amino acids with a molecular weight of ~260 kDa.

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🔬 Protein Info

Gene Symbol	NAV12PROTEIN
Chromosome	2q24
Protein Type	Channel
Function	is a voltage-gated sodium channel (NaV1.
Primary Expression	inhibitory interneurons, particularly parvalbumin-positive (PV+) and somatostatin-positive (SST+) subtypes, which are essential for maintaining proper
Molecular Weight	260 kDa
Amino Acids	2000 aa
GeneCards	NAV12PROTEIN
Human Protein Atlas	NAV12PROTEIN
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Nav1.1 Sodium Channel

protein · 2694 words

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Pathway Diagram

graph TD
    NAV12PROTEIN["NAV12PROTEIN"]
    neurodegeneration["neurodegeneration"]
    NAV12PROTEIN -->|"implicated_in"| neurodegeneration
    style NAV12PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning NAV12PROTEIN in their description or question text

No additional research found