Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEURD1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | NEURD1 |
| Full Name | N-terminal EGF Like Domain Calcium Binding Protein 1 |
| Aliases | Gene profile for NEURD1 |
| Chromosome | 19p13.3 |
| Function | is a neuronal protein characterized by the presence of EGF-like domains and calcium-binding motifs. |
| Subcellular Localization | and function ### Splice Variants Multiple NEURD1 isoforms have been identified |
| GeneCards | NEURD1 |
| Human Protein Atlas | NEURD1 |
| N-terminal signal peptide | Directs secretion and membrane targeting |
| Calcium-binding EF-hand domains | Characteristic sequence motifs that confer calcium-sensing capability |
| C-terminal region | Regulatory sequences affecting protein localization and function |
| Full-length isoform | Contains all functional domains |
| Shorter isoforms | Alternative splicing generates variants with different domain compositions |
| Tissue-specific variants | Brain-enriched and peripheral tissue variants |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
NEURD1["NEURD1"]
neurodegeneration["neurodegeneration"]
NEURD1 -->|"implicated_in"| neurodegeneration
style NEURD1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
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Experimental studies targeting or related to this entity
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NEURD1 in their description or question text
No additional research found