Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NFASC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | NFASC |
| Full Name | Neurofascin |
| Chromosome | 1q32.1 |
| Function | is a member of the L1 family of cell adhesion molecules (L1-CAMs). |
| Molecular Weight | 180 kDa |
| Amino Acids | 1245 aa |
| Exons | 35 |
| UniProt ID | [Q14807](https://www.uniprot.org/uniprot/Q14807) |
| Ensembl ID | ENSG00000163508 |
| OMIM | 609014 |
| GeneCards | NFASC |
| Human Protein Atlas | NFASC |
| NFASC155 | Glial isoform, expressed by oligodendrocytes |
| NFASC140 | Alternative isoform |
| NFASC164 | Brain-enriched isoform |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
NFASC["NFASC"]
neurodegeneration["neurodegeneration"]
NFASC -->|"implicated_in"| neurodegeneration
style NFASC fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NFASC in their description or question text
No additional research found