gene

NFAT4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NFAT4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

0Debates

Summary

NFAT4 is a calcium-dependent transcription factor regulating synaptic plasticity, neuroinflammation, and neuronal survival in neurodegenerative diseases.

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🧬 Gene Info

Gene Symbol	NFAT4
Full Name	Nuclear Factor of Activated T-cells 4
Chromosome	14q11.2.
Protein Type	Transcription Factor
Function	Calcium influx through voltage-gated channels or NMDA receptors
Molecular Weight	120 kDa
Amino Acids	073 aa
Exons	11
Pathways	NF-κB
UniProt ID	Q12918
NCBI Gene ID	4776
Ensembl ID	ENSG00000100868
OMIM	601065
GeneCards	NFAT4
Human Protein Atlas	NFAT4
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: NFAT4 — AlphaFold Q12918 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

NFAT4 — Nuclear Factor of Activated T-cells 4

gene · 2496 words

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Pathway Diagram

graph TD
    NFAT4["NFAT4"]
    neurodegeneration["neurodegeneration"]
    NFAT4 -->|"implicated_in"| neurodegeneration
    style NFAT4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NFAT4 in their description or question text

No additional research found