NHLRC1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolNHLRC1
NameNHL repeat containing E3 ubiquitin protein ligase 1
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2).[provided by RefSeq, Mar 2010].

This is an externally resolved entity

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