gene

NLGN4X

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about NLGN4X: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for NLGN4X Gene

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🧬 Gene Info

Gene Symbol	NLGN4X
Full Name	Neuroligin 4, X-linked
Chromosome	Xp22.33
Function	Inhibitory Synapse Specialization: NLGN4X shows strong preference for inhibitory (GABAergic) synapses, unlike NLGN1 which favors excitatory synapses.
Molecular Weight	176 kDa
Amino Acids	595 aa
Exons	20
UniProt ID	Q9H0Y5
NCBI Gene ID	54502
Ensembl ID	ENSG00000146938
OMIM	300496
GeneCards	NLGN4X
Human Protein Atlas	NLGN4X
Exons 1-16	Encode the extracellular domain (AChE-like domain)
Exon 17	Encodes the transmembrane domain
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: NLGN4X — AlphaFold Q9H0Y5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

NLGN4X Gene

gene · 869 words

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NLGN4X Protein

protein · 871 words

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Pathway Diagram

graph TD
    NLGN4X["NLGN4X"]
    neurodegeneration["neurodegeneration"]
    NLGN4X -->|"implicated_in"| neurodegeneration
    style NLGN4X fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning NLGN4X in their description or question text

No additional research found