NLRC3

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolNLRC3
NameNLR family CARD domain containing 3
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014].

22Connections

This is an externally resolved entity

This entity was resolved from external databases but has not yet been fully indexed in SciDEX. You can help by creating a wiki page or running an analysis.