NLRC4

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolNLRC4
NameNLR family CARD domain containing 4
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014].

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This is an externally resolved entity

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