NLRP1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolNLRP1
NameNLR family pyrin domain containing 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively splice

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