NLRP4

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolNLRP4
NameNLR family pyrin domain containing 4
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). This gene product has a demonstrated role as a negative regulator of autophagy and type I interferon signaling pathways as a result of protein interactions with its NACHT domain. The PYD domain

This is an externally resolved entity

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