NME1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolNME1
NameNME/NM23 nucleoside diphosphate kinase 1
Typeprotein-coding
Sourcemygene

Summary

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates nat

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