gene

NOB1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NOB1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Gene page for NOB1 - Nin1 Binding Protein 1 involved in ribosome biogenesis and linked to neurodegeneration

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🧬 Gene Info

Gene Symbol	NOB1
Full Name	NIN1 Binding Protein 1
Aliases	Gene page for NOB1
Chromosome	16q22.1
Function	encodes a critical protein involved in ribosome biogenesis and the maturation of the 40S ribosomal subunit.
Subcellular Localization	Nucleolus: Primary location for ribosome biogenesis
Molecular Weight	52 kDa
Amino Acids	465 aa
UniProt ID	Q9ULM3
NCBI Gene ID	28976
Ensembl ID	ENSG00000141101
OMIM	607772
GeneCards	NOB1
Human Protein Atlas	NOB1
N-terminal region	Contains the NIN1 binding domain
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: NOB1 — AlphaFold Q9ULM3 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

NOB1 — NIN1 Binding Protein 1

gene · 1497 words

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NOB1 Protein — NinOne Binding Protein 1

protein · 2134 words

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Pathway Diagram

graph TD
    NOB1["NOB1"]
    neurodegeneration["neurodegeneration"]
    NOB1 -->|"implicated_in"| neurodegeneration
    style NOB1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NOB1 in their description or question text

No additional research found