NOSTRIN

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolNOSTRIN
Namenitric oxide synthase trafficking
Typeprotein-coding
Sourcemygene

Summary

Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004].

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