gene

NOX5

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about NOX5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for NOX5 Gene

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🧬 Gene Info

Gene Symbol	NOX5
Full Name	NADPH Oxidase 5
Chromosome	15q21.3
Function	is an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight	93 kDa
Amino Acids	755 aa
UniProt ID	[Q96PH1](https://www.uniprot.org/uniprot/Q96PH1)
Ensembl ID	ENSG00000195226
OMIM	607610
GeneCards	NOX5
Human Protein Atlas	NOX5
N-terminal EF-hand domains (4×)	Calcium-binding motifs that sense intracellular calcium concentrations
Transmembrane domains (6×)	Anchor the protein to cellular membranes
dehydrogenase domain	FAD and NADPH binding site for electron transfer
C-terminal region	Contains the heme-binding pocket
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

NOX5 Gene

gene · 1022 words

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Pathway Diagram

graph TD
    NOX5["NOX5"]
    neurodegeneration["neurodegeneration"]
    NOX5 -->|"implicated_in"| neurodegeneration
    style NOX5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning NOX5 in their description or question text

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