NRF1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolNRF1
Namenuclear respiratory factor 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared sy

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This is an externally resolved entity

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