Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NRG2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | NRG2 |
| Full Name | Neuregulin 2 |
| Aliases | Page for NRG2, Neuregulin-2 |
| Chromosome | 5q31.2 |
| Function | NRG2 signals through ErbB3 and ErbB4 receptors to regulate nervous system development and function |
| Primary Expression | hippocampal interneurons where it regulates synaptic plasticity and spatial memory formation |
| Molecular Weight | 70 kDa |
| Amino Acids | 642 aa |
| Ensembl ID | ENSG00000158457 |
| GeneCards | NRG2 |
| Human Protein Atlas | NRG2 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
NRG2["NRG2"]
neurodegeneration["neurodegeneration"]
NRG2 -->|"implicated_in"| neurodegeneration
style NRG2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NRG2 in their description or question text
No additional research found