Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NTKR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | NTKR1 |
| Full Name | NTRK1 |
| Chromosome | 1q23.1 [@megarbane2022] |
| Protein Type | Gene |
| Function | NTRK1 encodes TrkA (Tropomyosin receptor kinase A), the primary receptor for nerve growth factor (NGF). |
| UniProt ID | P04629 |
| NCBI Gene ID | 4914 |
| Ensembl ID | ENSG00000159479 |
| GeneCards | NTKR1 |
| Human Protein Atlas | NTKR1 |
| Associated Diseases | Congenital Insensitivity to Pain with Anhidrosis (CIPA), Alzheimer's Disease |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
NTKR1["NTKR1"]
neurodegeneration["neurodegeneration"]
NTKR1 -->|"implicated_in"| neurodegeneration
style NTKR1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NTKR1 in their description or question text
No additional research found