protein

NTN2PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NTN2PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Netrin 2 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	NTN2PROTEIN
Full Name	Netrin-2 (NTN2)
Protein Family	Netrin family, Laminin superfamily
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	the developing nervous system with patterns that complement netrin-1, suggesting both overlapping and distinct functions
Subcellular Localization	</td><td>Extracellular, secreted</td></tr>
Molecular Weight	~70 kDa (607 amino acids)
Amino Acids	607 aa
UniProt ID	Q8WWS8
GeneCards	NTN2PROTEIN
Human Protein Atlas	NTN2PROTEIN
N-terminal domain (NTN)	Receptor-binding region critical for DCC/UNC-5 binding
Laminin VI (LamNT) domain	Homologous to laminin short arms
Laminin IV (LamAC) domain	C-terminal laminin-like modules
C-terminal heparin-binding domain	Mediates interactions with cell surface
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: NTN2PROTEIN — AlphaFold Q8WWS8 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Netrin 2 Protein

protein · 1028 words

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Pathway Diagram

graph TD
    NTN2PROTEIN["NTN2PROTEIN"]
    neurodegeneration["neurodegeneration"]
    NTN2PROTEIN -->|"implicated_in"| neurodegeneration
    style NTN2PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning NTN2PROTEIN in their description or question text

No additional research found