Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NTNG1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Gene Symbol | NTNG1 |
| Protein Type | Gene |
| Function | NTNG1 (Netrin G1) encodes a member of the netrin family of axon guidance molecules. |
| Primary Expression | excitatory glutamatergic neurons - Lower expression in inhibitory GABAergic neurons - Developmental expression peaks during synap |
| GeneCards | NTNG1 |
| Human Protein Atlas | NTNG1 |
| [LRP1](/proteins/lrp1)/LRP2 | Neurexins and their alternative receptors LRP1 and LRP2 mediate postsynaptic responses to presynaptic NTNG1 |
| PTPσ | Protein tyrosine phosphatase sigma interacts with NTNG1 to regulate synaptic development |
| CASK | Scaffold protein that links NTNG1 to synaptic signaling complexes |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
NTNG1["NTNG1"]
neurodegeneration["neurodegeneration"]
NTNG1 -->|"implicated_in"| neurodegeneration
style NTNG1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NTNG1 in their description or question text
No additional research found