Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NUP54: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | NUP54 |
| Full Name | Nucleoporin 54 |
| Chromosome | 4p13 |
| Function | NUP54 forms the central channel scaffold of the nuclear pore complex through heterodimerization with NUP58: |
| UniProt ID | [Q7Z417](https://www.uniprot.org/uniprot/Q7Z417) |
| Ensembl ID | ENSG00000125787 |
| GeneCards | NUP54 |
| Human Protein Atlas | NUP54 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
NUP54["NUP54"]
neurodegeneration["neurodegeneration"]
NUP54 -->|"implicated_in"| neurodegeneration
style NUP54 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NUP54 in their description or question text
No additional research found