Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Neuroinflammatory Priming: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| HMGB1 | regulates | protein | 0.95 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflam | 0.617 | neurodegeneration | What are the mechanisms by which gut mic |
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Microglia-Mediated Neuroinflammation: A Potential Target for the Treatment of Ca [PMID:35642214] | Wang M, Pan W, Xu Y, Zhang J, Wan J, Jia | J Inflamm Res | 2022 | 1 |
| Podocyte TLR4 deletion alleviates diabetic kidney disease through prohibiting PK [PMID:40659086] | Li Z, Tan D, Lin J, Zhang T, Liu B et al | J Adv Res | 2026 | 0 |
| Celastrol treatment attenuates the inflammatory response in Alzheimer's disease [PMID:40762111] | Cao F, Zhang P, Zheng Z, Wang P, Wang Y | Neurol Res | 2026 | 0 |
| CircCramp1l targets the miR-532-3p/HMGB1/Drp1 axis to regulate allergic rhinitis [PMID:41519399] | Zhang Y, Wang J, Song Y, Chai J, Li L et | Biochem Pharmacol | 2026 | 0 |
| Panax ginseng-derived Exosome-like Nanoparticles Prevent LPS-induced Septic Shoc [PMID:41530048] | Kim Y, Kim YK, Lee S, Kim M, Lee SW et a | Mol Pharm | 2026 | 0 |
| Neuronal TLR4 upregulation activates the cGAS-STING pathway to induce ferroptosi [PMID:41702081] | Qin H, Yang L, Du J, Xu X, Chen Z et al. | Int Immunopharmacol | 2026 | 0 |
| 2'-Fucosyllactose Alleviates Metabolic Hypertension in Mice via Gut Microbiota M [PMID:41926238] | Chen J, Liang S, Liu D, Yang S, Yan Q et | J Agric Food Chem | 2026 | 0 |
| Leveraging intraperitoneal delivery of toll-like receptor agonists to treat peri [PMID:41926324] | Yan H, Chia D, Ernst S, Demuytere J, Cos | Expert Opin Drug Deliv | 2026 | 0 |
| Small-molecule PCSK9 inhibition enhances BBB amyloid-β clearance and suppresses [PMID:41927877] | Miao J, Wang J, Zhou W, Guo J | Sci Rep | 2026 | 0 |
| Anti-carbamylated protein antibodies stabilize carbamylated Histone H3 to promot [PMID:41930627] | Nakabo S, Hanata N, Patino-Martinez E, H | Arthritis Rheumatol | 2026 | 0 |
| In silico design of a novel multi-epitope mRNA vaccine candidate for BtHKU5-CoV- [PMID:41931545] | Zheng N, Xu Y | PLoS Negl Trop Dis | 2026 | 0 |
| Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF. [PMID:41931597] | Ma B, Lyu W, Rizk J, Han X, Kjær M et al | Sci Immunol | 2026 | 0 |
| Reverse vaccinology and immunoinformatics Approaches Driven designing of a Novel [PMID:41934706] | Siddiquee NH, Al Mamun MA, Dremit TI, Ul | Hum Immunol | 2026 | 0 |
| MEX3B aggravates osteoarthritis progression by post-transcriptionally activating [PMID:41935341] | Fu Z, Huang Y, Zhang S, Chen J | J Orthop Surg Res | 2026 | 0 |
| Hierarchical Targeting of TREM2(+) Myeloid Cells via Acid-Triggered OMVs Reprogr [PMID:41945876] | Chen F, Xue Y, Ma X, Chen L, Shao Z et a | Adv Sci (Weinh) | 2026 | 0 |
| Molecular characterization and immunoinformatics-based design of a multi-epitope [PMID:41949632] | Asim M, Makki HH | Antonie Van Leeuwenhoek | 2026 | 0 |
| Zearalenone causes female reproductive lipotoxicity through the ERα-CD36/TLR4 si [PMID:41957128] | Dai C, Fu W, Huang Y, Li T, Ma Z et al. | Commun Biol | 2026 | 0 |
| Protective effect of nebivolol on bleomycin-induced lung fibrosis via suppressin [PMID:41960705] | Morsy MA, Abdel-Gaber SA, Abed El Baky M | Immunopharmacol Immunotoxicol | 2026 | 0 |
| Astrocytic calcium-dependent enzyme PAD2 governs microglia activity to exacerbat [PMID:41962542] | Zhang J, Huang Y, Chen Y, Zhang Y, Chen | Immunity | 2026 | 0 |
| Inhibition of TLR4/TRAF6/NF-κB pathway by empagliflozin mitigates concanavalin A [PMID:41964671] | El-Kashef DH, Shawky NO, Mahdi L, Sewila | Naunyn Schmiedebergs Arch Phar | 2026 | 0 |