P2RY12

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolP2RY12
Namepurinergic receptor P2Y12
Typeprotein-coding
Sourcemygene

Summary

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing result

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