PANK1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPANK1
Namepantothenate kinase 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53

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